set·back ˈsetˌbak/ noun 1. a reversal or check in progress. synonyms: problem, difficulty, hitch, complication, upset, disappointment, misfortune, mishap, reversal;blow, stumbling block, hurdle, hinderance, impediment, obstruction, delay, holdup. informal: glitch, hiccup re·set rēˈset/ transition verb 1. set again or differently. Synonyms: changed, renew, revised, regenerated, transformed, established, corrected, revolutionized, improved, reconstructed, amended, reworked …